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Postdoctoral Position: Hypoxia & Antiviral Immunity in the Gut
Join the Boulant Lab at the University of Florida to investigate the molecular mechanisms regulating polarized sorting in epithelial cells! Our NIH-funded project explores how the gut's natural low-oxygen environment impacts intestinal epithelial cell responses to enteric viruses. We're seeking a motivated postdoc to unravel how hypoxia alters innate immune signaling pathways and influences viral infection outcomes.
The successful candidate will investigate the mechanisms of hypoxia-dependent regulation of antiviral immunity using gene editing, advanced microscopy, and innovative organoid/microfluidic models. Work with cutting-edge techniques in a collaborative environment to understand how oxygen gradients in the crypt/villus axis affect viral susceptibility. This position includes opportunities to develop novel therapeutic strategies targeting cellular responses to hypoxia.
Postdoctoral Position: Molecular Mechanisms of Polarized Sorting in Epithelial Cells
Join the Boulant Lab at the University of Florida to investigate how epithelial cells establish and maintain polarity! Our DFG/NSF-funded collaboration with Francesca Bottanelli at Freie Universität Berlin explores the molecular mechanisms regulating the clathrin/AP-1/ARF-1 sorting machinery in polarized epithelial cells. We're seeking a motivated postdoc to unravel how clathrin light chains and adaptor proteins coordinate cargo sorting to apical and basolateral membranes.
The ideal candidate will have experience in cell biology, molecular biology techniques, and microscopy. You'll have the opportunity to conduct cutting-edge research using gene editing, super-resolution microscopy, and advanced proteomics. This position includes travel to our collaborator's lab in Berlin for specialized imaging experiments.
Apply now to be part of groundbreaking research that will advance our understanding of fundamental cell biological processes relevant to numerous human diseases!
